Dr. Ants Toi is a Professor of Radiology and of Obstetrics and Gynecology at the University of Toronto. He received his radiology training at the University of Toronto and Harvard, Boston.
His work history includes Harvard, Boston, McMaster University Medical Center in Hamilton, University Health Network, and University of Toronto.
His current work lies in the area of Diagnostic Imaging at University Health Network, Mount Sinai Hospital, and Women’s College Hospital.
Dr. Toy’s special interests include diagnostic ultrasound, especially prenatal fetal diagnosis and prostate cancer.
- Prostate biopsy in the era of MRI-targeting: towards a judicious use of additional systematic biopsy
CONCLUSION: Not all men benefit equally from the combination of SBx and MRI-TBx. SBx avoidance in men with PI-RADS 5 and/or previous negative biopsy […]
- Avoiding Unnecessary Biopsy: MRI-based Risk Models versus a PI-RADS and PSA Density Strategy for Clinically Significant Prostate Cancer
Background In validation studies, risk models for clinically significant prostate cancer (csPCa; Gleason score ≥3+4) combining multiparametric MRI […]
- Gleason grade 5 prostate cancer: sub-patterns and prognosis
Since the conception of the Gleason grading system, several modifications have been made, including the definition of Gleason pattern 5 (GP5) and its […]
- Reply by Authors
- Does the Visibility of Grade Group 1 Prostate Cancer on Baseline Multiparametric Magnetic Resonance Imaging Impact Clinical Outcomes?
CONCLUSIONS: Men with positive multiparametric magnetic resonance imaging and GG1 prostate cancer on magnetic resonance imaging targeted biopsy are […]
- Utility of digital rectal examination in a population with prostate cancer treated with active surveillance
CONCLUSIONS: We believe DRE should still be used as part of AS and can predict the presence of csPCa, even with low PSA values. A suspicious nodule […]
- Correction to: Correlation of 3T multiparametric prostate MRI using prostate imaging reporting and data system (PIRADS) version 2 with biopsy as reference standard
Unfortunately the article was published with a spell error in the co-author name "Hassan Maan". The correct co-author name should be "Hassaan Maan".
- Methylation Markers in Prostate Biopsies Are Prognosticators for Late Biochemical Recurrence and Therapy after Surgery in Prostate Cancer Patients
After diagnosis of prostate cancer is confirmed by a positive biopsy, the tumor may be surgically removed via radical prostatectomy (RP). However, […]
- Extraprostatic Extension in Core Biopsies Epitomizes High-risk but Locally Treatable Prostate Cancer
CONCLUSIONS: EPE on PB is an infrequent finding that is strongly associated with high-risk clinicopathologic prognostic features that accurately […]
- Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry
The original version of this Article contained an error in the spelling of the author Manuela Gago-Dominguez, which was incorrectly given as Manuela […]
- Fetal myelomeningocele surgery: Only treating the tip of the iceberg
CONCLUSION: Only a minority of fMMC cases will ultimately undergo fetal surgery. These numbers support the centralization of care in expert centers.
- Germline variation at 8q24 and prostate cancer risk in men of European ancestry
Chromosome 8q24 is a susceptibility locus for multiple cancers, including prostate cancer. Here we combine genetic data across the 8q24 […]
- Correlation of 3T multiparametric prostate MRI using prostate imaging reporting and data system (PIRADS) version 2 with biopsy as reference standard
CONCLUSION: PIRADS ≥ 3 had high specificity and high negative predictive value for csPCa using biopsy results as the standard of reference. The […]
- Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been […]
- Evaluation of an Aggressive Prostate Biopsy Strategy in Men Younger than 50 Years
CONCLUSIONS: Our results justify adopting an aggressive prostate biopsy strategy in men younger than 50 years with prostate specific antigen 1.5 […]
- Role of Magnetic Resonance Imaging Targeted Biopsy in Detection of Prostate Cancer Harboring Adverse Pathological Features of Intraductal Carcinoma and Invasive Cribriform Carcinoma
CONCLUSIONS: Multiparametric magnetic resonance imaging/ultrasound fusion targeted biopsy was associated with significantly increased detection of […]
- Creation and internal validation of a biopsy avoidance prediction tool to aid in the choice of diagnostic approach in patients with prostate cancer suspicion
CONCLUSION: These prediction models may help guide clinicians in avoiding unnecessary initial and repeat biopsies in men unlikely to harbor CSPC. […]
- Modern-day prostate cancer is not meaningfully associated with lower urinary tract symptoms: Analysis of a propensity score-matched cohort
CONCLUSIONS: Modern PCa does not appear to be associated with worse LUTS compared to benign prostates of the same size. Outlet obstruction is likely […]
- Germline Mutations in the Kallikrein 6 Region and Predisposition for Aggressive Prostate Cancer
CONCLUSIONS: Our fine-mapping study has identified novel loci in the KLK 6 region strongly associated with aggressive PCa.
- Psychosocial determinants for treatment decisions in familial retinoblastoma
- Development and external validation of a biopsy-derived nomogram to predict risk of ipsilateral extraprostatic extension
CONCLUSION: We developed and externally validated a nomogram that predicts the risk of ipsilateral EPE based on commonly used preoperative markers. […]
- Congenital limb deficiencies with vascular etiology: Possible association with maternal thrombophilia
Congenital limb deficiency defects (LDDs) are etiologically heterogeneous. Acquired causes include amniotic bands, teratogens exposure, and chorionic […]
- Limitations in Predicting Organ Confined Prostate Cancer in Patients with Gleason Pattern 4 on Biopsy: Implications for Active Surveillance
CONCLUSIONS: The quantitative percent of Gleason pattern 4 helps predict advanced disease and Gleason score 7 (3 + 4) is associated with worse […]
- The pathology of incipient polymicrogyria
CONCLUSIONS: The array of histological changes encompasses all tissue elements of the affected brains, early in the evolution polymicrogyria. […]
- The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition
Multiple glycosyltransferases are essential for the proper modification of alpha-dystroglycan, as mutations in the encoding genes cause […]
- Choice of Formula and Accuracy of Fetal Weight Estimation in Small-for-Gestational-Age Fetuses
CONCLUSIONS: Sonographic models in current use for fetal weight estimation in SGA fetuses have significant errors, and their performance varies for […]
- Maternal Cardiac Output and Fetal Doppler Predict Adverse Neonatal Outcomes in Pregnant Women With Heart Disease
CONCLUSIONS: Decline in maternal cardiac output during pregnancy and abnormal umbilical artery Doppler flows independently predict neonatal […]
- An Increase in Gleason 6 Tumor Volume While on Active Surveillance Portends a Greater Risk of Grade Reclassification with Further Followup
CONCLUSIONS: While Gleason 6 prostate cancer has a favorable natural history, it appears that patients on active surveillance who experience volume […]
- Magnetic resonance imaging detected prostate evasive anterior tumours: Further insights
CONCLUSION: PEATS tumours are found late and are disproportionally high grade tumours. Careful consideration to MRI testing should be given to men at […]
- Infectious complications following transrectal ultrasound-guided prostate biopsy: a Canadian tertiary cancer center experience